What really trigger pattern hair loss in women?
From the standpoint of vulnerability, the inheritance pattern in female pattern hair loss is polygenic, and the onset of disease incidence and parallel to that observed in men. The disorder begins with sensitive hair follicles, where dihydrotestosterone, DHT binds to androgen receptors form a molecular trigger that sets in motion the process of hair loss.
The 5-alpha dihydrotestosterone hormone-receptor complex to the nucleus of the cells sensitive hair follicles, initiating a gene activation program to a gradual transformation of large terminal follicles to miniaturized follicles began. This process happens within a predetermined genetic anatomy, or the pattern of the scalp. This pattern of outer hair remains unaffected. That is why this condition is called pattern hair loss.
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